Publications

Selected Publications

• Oldfield TJ, Gonçalves Torres R, Baier RE, Renn R, and Trentini DB (2026). Principles of ribosome-associated protein quality control during the synthesis of CFTR. EMBO J. https://doi.org/10.1038/s44318-026-00883-0
• Batonnet-Pichon S, Delort F, Lilienbaum A, Berwanger C, Schultheis D, Schlötzer-Schrehardt U, Schmidt A, Uebe S, Baiche Y, Eisenack TJ, Trentini DB, Mallek M, Mill L, Ferreiro A, Eberhard B, Lücke T, Krüger M, Thiel C, Schröder R and Clemen CS (2025). R405W Desmin Knock-In Mice Highlight Alterations of Mitochondria, Protein Quality Control and Myofibrils in Myofibrillar Myopathy. J Cachexia Sarcopenia Muscle 16(6): e70094.DOI: 10.1002/jcsm.70094. https://doi.org/10.1002/jcsm.70094
• Eisenack TJ, and Trentini DB (2023). Ending a bad start: Triggers and mechanisms of co-translational protein degradation. Front Mol Biosci. 9: 1089825. https://doi.org/10.3389/fmolb.2022.1089825
• Trentini DB, Pecoraro M, Tiwary S, Cox J, Mann M, Hipp MS, and Hartl FU (2020) Role for ribosome-associated quality control in sampling proteins for MHC class I-mediated antigen presentation. Proc Natl Acad Sci U S A., 117(8): 4099-4108­ https://doi.org/10.1073/pnas.1914401117
  
  Winner of the Junior Scientists' Publication Award 2020 of the Max Planck Institute of Biochemistry https://twitter.com/MPI_Biochem/status/1284128946192289795?s=20 
  Marked for interesing hypothesis and new finding in in the Faculty Opinions platform: https://facultyopinions.com/prime/737354205
  See the comment about this paper at the Nature Research Microbiology Community: https://communities.springernature.com/posts/journal-club-how-are-viral-peptides-presented-to-the-immune-system. Many thanks to Marcin Suskiewicz for highlighting our story!
• Trentini DB*, Suskiewicz MJ*, Heuck A, Kurzbauer R, Deszcz L, Mechtler K, and Clausen T (2016) Arginine phosphorylation marks proteins for degradation by a Clp protease. Nature.539: 48. https://doi.org/10.1038/nature20122  ­*equal contribution
  
  This paper has been graded “exceptional” 4 times in the F1000Prime/Faculty Opinions platform! See opinions at: https://facultyopinions.com/prime/726854959
  Discussed in Nature’s News and Views https://www.nature.com/articles/539038a and in Nature Reviews Microbiology https://www.nature.com/articles/nrmicro.2016.159
  Read the “behind the paper” story at https://communities.springernature.com/posts/nosing-out-a-degradation-signal.
• Trentini DB, Fuhrmann J, Mechtler K, and Clausen T (2014) Chasing phosphoarginine proteins: development of a selective enrichment method using a phosphatase trap. Mol Cell Proteomics. 13: 1953-1964. https://doi.org/10.1074/mcp.O113.035790
• Schmidt A*, Trentini DB*, Spiess S, Fuhrmann J, Ammerer G, Mechtler K, and Clausen T (2014) Quantitative phosphoproteomics reveals the role of protein arginine phosphorylation in the bacterial stress response. Mol Cell Proteomics.13: 537-550. https://doi.org/10.1074/mcp.M113.032292  ­*equal contribution
  
  One of the highlights of Mol Cell Proteomics Vol. 13, Issue 2
• Fuhrmann J, Mierzwa B, Trentini DB, Spiess S, Lehner A, Charpentier E, Clausen T (2013) Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. Cell Rep. 3(6): 1832-9. https://doi.org/10.1016/j.celrep.2013.05.023
• Sant'Anna FH*, Trentini DB*, de Souto Weber S, Cecagno R, da Silva SC, Schrank IS. (2009) The PII superfamily revised: a novel group and evolutionary insights. J Mol Evol. 68(4): 322-36. https://doi.org/10.1007/s00239-009-9209-6  ­*equal contribution